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Research 

Research

Thesis 

Bachelor of Science:

Title: An investigation of GABRA1 protein tertiary structure models estimate folding free energy (ΔG) from GABRA1 holding five missense SNPs and haplotypes for epilepsy.

Scientific publications and Manuscripts

  • Bhowmik, Sagar & Akhter, Md. (2020). A Computational Molecular Docking Studies on the Tryparedoxin Peroxidase of Leishmania donovani responsible for visceral leishmaniasis in human. Letters in Drug Design & Discovery. 17. 10.2174/1570180817999200730171556.

  • Bhowmik S, Islam KK, Samrat MSK, Mandal C and Awal SM (2020). A comprehensive in silico drug repositioning to carbamazepine based causative missense SNP c.965C>A in GABRA1 for Juvenile Myoclonic Epilepsy. (Under consideration for publication in Current Computer-Aided Drug Design)

  • Bhowmik S, Akhter SM and Samrat MSK (2019). A Comprehensive in silico study for the Identification of Therapeutic target against Peripheral Neuropathic Pain in human. (Under consideration for publication in In Silico Pharmacology- Springer)

  • Samrat MSK and Bhowmik S (2020). A comprehensive in silico study for the identification of therapeutic target against addiction especially addictive behavior in human. (Under consideration for publication in Letters in Drug Design & Discovery)

  • Kakon O and Bhowmik S (2020). In silico analysis of polyphenols as inhibitors of acetylcholinesterase (AChE) enzyme in Alzheimer’s disease treatment. (Manuscript in preparation).

  • Alam TU and Bhowmik S (2020). Prediction of functional T-cell Epitopes in the Zika virus polyprotein: An in silico approach. (Manuscript in preparation).

Conference talk and Refereed Conference Abstracts

  • Bhowmik S, Islam KK and Samrat MSK (2019). A comprehensive in silico drug design to the target a missense SNP of GABRA1 responsible for idiopathic generalized epilepsy in human. (Abstract no BGPP-03 in International Conference on Advancement of Life Sciences, ICALS, MBSTU, Santosh, Tangail, Bangladesh)

  • Bhowmik S, Islam KK and Samrat MSK (2019). A comprehensive in silico study for the identification of therapeutic target against addiction especially addictive behavior in human. (Abstract no BGPP-09 in International Conference on Advancement of Life Sciences, ICALS, MBSTU, Santosh, Tangail, Bangladesh)

  • Samrat MSK and Bhowmik S (2019). In silico drug design to the target a non-synonymous SNP of ADH1C responsible for alcoholism in human. (Abstract no BGPP-01 in International Conference on Advancement of Life Sciences, ICALS, MBSTU, Santosh, Tangail, Bangladesh)

Ongoing Research Projects

  • Immunoinformatics study for epitope based vaccine design on major proteins of novel coronavirus (SARS-CoV-2).

  • In silico study for the identification of COVID-19 antiviral leads targeting main protease (Mpro)and papin-like protease (PLpro)

  • In silico drug design for dengue virus via NS2B/NS3 protein as a target of therapeutic interest” funded by Khulna University Research Cell (KURC).

  • Determination of Carcinogenic and Non-carcinogenic Metal Contaminants in Commercial Noodles of Bangladesh.

  • Health risk assessment of commercial noodles commonly consumed in Bangladesh.

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